Jul 4, 2016
Mobilizing mitochondria aids axon regeneration
In mature neurons, the axonal transport of mitochondria is suppressed by the expression of the mitochondrial anchoring protein syntaphilin. Zhou et al. reveal that enhancing mitochondrial transport in mature neurons rescues energy deficits and facilitates axon regeneration after injury. This biosights episode presents the paper by Zhou et al. from the July 4th, 2016, issue of The Journal of Cell Biology and includes an interview with the paper's senior author, Zu-Hang Sheng (National Institute of Neurological Disorders and Stroke, Bethesda, MD). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.
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The Rockefeller University Press