Jan 19, 2015
Tubulin transport pumps up cilia
The assembly of cilia and flagella requires the delivery of large amounts of tubulin to the growing ends of the organelles' microtubules. Craft et al. reveal that tubulin loading onto intraflagellar transport particles is specifically upregulated in growing cilia. This biosights episode presents the paper by Craft et al. from the January 19, 2015, issue of The Journal of Cell Biology and includes an interview with the paper's senior author, Karl Lechtreck (University of Georgia, Athens, GA). Produced by Caitlin Sedwick and Ben Short. See the associated paper in JCB for details on the funding provided to support this original research.
The Rockefeller University Press