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Dec 23, 2009

Mitotic spindle microtubules have long been thought to deliver a signal to the cell cortex that positions the cytokinetic cleavage furrow. A new study reveals that accurate cytokinesis still occurs in the absence of contact between microtubules and the plasma membrane, and suggests that multiple spatial cues combine to define the furrow’s location. This biosights episode presents the paper by von Dassow et al. from the December 14th, 2009 issue of the Journal of Cell Biology, and includes interviews with authors George von Dassow and Bill Bement. Produced by Eun Choi and Ben Short.



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The Rockefeller University Press